The concentration differences of dental caries induced organic acids which are produced after intake of sucrose and carbonated drinks

Jung-Eun Park   Jong-Hwa Jang1,*   

Department of Preventive and Social Dentistry, School of Dentistry, Kyung Hee University
1Department of Dental Hygiene, Hanseo University

Abstract

Objectives: This study aims to evaluate carbonated drinks induced dental caries with qualitative analysis and to compare with oral organic acids including lactate, acetate, propionate, formate, butyrate, pyruvate and valerate which cause caries when taking either 10% sucrose drinks or carbonated drinks. Methods: Saliva was collected from six study subjects before and after (start, 5, 10, 30 minutes) taking water intake upon (A) 10% sucrose intake, (B) 10% sucrose intake, and (C) carbonated drink intake, then they were centrifuged at 1,200 rpm followed by removing bacteria and enzymes with syringe filtering, performing a qualitative analysis with HPLC conductivity detection (GP50 gradient pump, ED 50 detector) after saliva pre-treatment under isocratic 100 mM NaOH mobile phase. Results: Higher risk of dental caries was evaluated in order of C>B>A, with the results of total oral organic acids’ concentration, lactates of organic acids and organic acids produced after 5 minutes from the 3 types of drinks intake. Conclusions: Carbonated beverages were estimated to develop higher dental caries induction than beverages containing 10% sucrose because of the high organic acid concentration in the mouth after its intake.

Acknowledgements

이 논문은 미래창조과학부의 재원으로 한국연구재단의 지원을 받아 수행된 기초연구 지원 사업임(2014R1A1A3051084와 2017R1A2B4012865).

Figures & Tables

Flow chart of study design