Department of Dental Hygiene, Wonkwang Health Science University1
Department of Preventive and Public Health Dentistry, College of dentistry, Wonkwang University2
Objectives: The purpose of this study was to examine the association between two major oral diseases and cardiovascular diseases. Methods: Data from the 6th Korean National Health and Nutrition Examination Survey (2013–2015) were used. The study included 12,754 adults, aged ≥19 years, who participated in the questionnaire survey of health related to hypertension, stroke, myocardial infarction, and angina pectoris as well as completed blood tests, anthropometry, and oral examination. Statistical analyses included complex sample frequency, complex sample general linear, complex sample cross-tabulation, and complex sample logistic regression analyses. Results: With respect to the number of Decayed-Missing-Filled-Teeth(DMFT ), patients with hypertension (DMFT 8.05), stroke (DMFT 8.66), and angina pectoris (DMFT 8.24) showed a DMFT score of >2, compared with those who did not have these diseases (p<0.05). Patients with hypertension, stroke, myocardial infarction, and angina pectoris presented an approximately 2.7, 3.5, 4, and 3 times higher incidence of periodontal diseases, respectively, than those who did not (p<0.05). Based on the analysis of the relationship between the number of DMFT and cardiovascular diseases, patients with cardiovascular diseases had a risk of 1.033 higher DMFT than those who did not (p<0.05). As per the analysis of the relationship between periodontal diseases and cardiovascular diseases, patients with cardiovascular diseases had a 2.969 higher risk of periodontaldiseasesthanthosewithout them (p<0.05). Conclusions: Two major oral diseases were found to be associated with cardiovascular diseases. Therefore, to prevent these major oral diseases in patients with cardiovascular diseases, oral hygiene management must be actively performed.
1. Naver. Cardiovascular disease[Internet]. [cited 2018 July 13]. Available from : https://terms.naver.com/entry.nhn?docId=927349&cid=51007&categoryId=51007.
2. Korea Statistics. Causes of Death Statistics in 2016. Daejeon: Korea Statistics; 2016: 1.
3. Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL, et al. Association between dental health and acute myocardial infarction. BMJ 1989 25;298(6676):779-81.
4. Emingil G, Buduneli E, Aliyev A, Akilli A, Atilla G. Association between periodontal disease and acute myocardial infarction. J Periodontol 2000;71(12):1882-6.
5. Hamasha AA, Hand JS, Levy SM. Medical conditions associated with missing teeth and edentulism in the institutionalized elderly. Spec Care Dentist 1998;18(3):123-7.
6. Choi YH, Suh IL, Nam JM, Oh DK, Son HK, Kwon HK. Associations of missing teeth with medical status. J Korean Acad Dent Health 2002;26(2):169-80.
7. Loesche WJ. Periodontal disease as a risk factor for heart disease. Compendium 1994;15(8):976-91.
8. Scannapieco FA. Position paper of the american academy of periodontology: periodontal disease as a potential risk factor for systemic diseases. J Periodontol 1998;69(7):841-50.
9. Ahn YB, Shin MS, Han DH, Sukhbaatar M, Kim MS, Shin HS, et al. Periodontitis is associated with the risk of subclinical atherosclerosis and peripheral arterial disease in Korean adults. Atherosclerosis 2016;251:311-8. https://doi.org/ 10.1016/j.atherosclerosis.2016.07.898.
10. Mattila KJ, Valtonen VV, Nieminen M, Huttunen JK. Dental infection and the risk of new coronary events: prospective study of patients with documented coronary artery disease. Clin Infect Dis 1995;20(3):588-92.
11. Grau AJ, Buggle F, Ziegler C, Schwarz W, Meuser J, Tasman AJ, et al. Association between acute cerebrovascular ischemia and chronic and recurrent infection. Stroke 1997;28(9):1724-9.
12. Ylöstalo PV, Järvelin MR, Laitinen J, Knuuttila ML. Gingivitis, dental caries and tooth loss: risk factors for cardiovascular diseases or indicators of elevated health risks. J Clin Periodontol 2006;33(2):92-101.
13. Joshipura KJ, Rimm EB, Douglass CW, Trichopoulos D, Ascherio A, Willett WC. Poor oral health and coronary heart disease. J Dent Res 1996;75(9):1631-6.
14. Ministry of Health and Welfare, Korea Centers for Disease Control and Prevention. Korea health statistics 2015 : Korea National Health and Nutrition Examination Survey(KNHANES Ⅵ-3). Cheongju: Korea Centers for Disease Control and Prevention; 2015: 295-6.
15. Korean statistical information service. Outpatient benefits by frequency of disease 2016[Internet]. [cited 2018 July 21]. Available from :http://kosis.kr/statHtml/statHtml.do?orgId=350&tblId=DT_35001_A083111&vw_cd=MT_ZTITLE&list_id=350_35001_6&seqNo=&lang_mode=ko&language=kor&obj_var_id=&itm_id=&conn_path=MT_ZTITLE.
16. Umino M, Nagao M. Systemic diseases in elderly dental patients. Int Dent J 1993;43(3):213-8.
17. Choe SL, Min SG, Choe MG. Retrospective study on prognosis of the medically compromised patients in department of oral and maxillofacial surgery. Maxillofac Plast Reconstr Surg 2003;25(5):439-47.
18. Naver. Hypercholesterolemia[Internet]. [cited 2018 July 22]. Available from : https://terms.naver.com/entry.nhn?docId=487014&cid=60408&categoryId=55558.
19. Beck J, Garcia R, Heiss G, Vokonas PS, Offenbacher S. Periodontal disease and cardiovascular disease. J Periodontol 1996;67(Suppl 10S):1123-37. https://doi.org/ 10.1902/jop.1996.67.10s.1123.
20. Na HS, Chung J. Contribution of periodontal disease in atherosclerosis. J Bacteriol Virol 2015;45(2):165-70. https://doi.org/10.4167/jbv.2015.45.2.165
21. Sim SJ, Moon JY, Park SW, Kim SH, Jang SJ, Rho JH. Oral health status in stroke patients. Korean J Stroke 2007;9(2):142-7.
22. Hong SP, Park EY, Lee HK. Oral condition in cardiovascular disease patients. Yeungnam University J of Med 2007;24(2S):598-605.
23. Kim EK, Kim MS, Lee HK. A study on the oral health and oral health related quality of life of stroke patients in a rehabilitation ward: A pilot study. J Dent Hyg Sci 2016;16(2):127-33. https://doi.org/10.17135/jdhs.2016.16.2.127
24. Cheon HW, Yu MS, Choi MH. The association of oral diseases and chronic diseases in Korean adult population. J Korean Soc Dent Hyg 2012;12(2):235-49. https://doi.org/10.13065/jksdh.2012.12.2.235
25. Kim CS, Choi YK. Survey of adults` perceptions of the association between chronic diseases and oral health. J Dent Hyg Sci 2017;17(1):12-9. https://doi.org/10.17135/jdhs.2017.17.1.12
26. Cha ES, Son KY, Yun JM, Chung WJ, Cho BL, Jin BH. Associations between atherosclerosis and periodontitis, physical health and dental care: a pilot study. J Korean Acad Dent Health 2017;41(4):274-81. https://doi.org/10.11149/jkaoh.2017.41.4.274
27. Reichert S, Schlitt A, Beschow V, Lutze A, Lischewski S, Seifert T, et al. Use of floss/interdental brushes is associated with lower risk for new cardiovascular events among patients with coronary heart disease. J Periodontal Res 2015;50(2):180-8. https://doi.org/10.1111/jre.12191. Epub 2014 May 14.